Kakuran no Mushi is one of the 63 creepy germs written in Harikikigaki, a book of medical knowledge written in 1568 by an unknown resident of Osaka. This tiny malevolent creature is believed to have caused human illness during the 16th century in Japan.
Kakuran no Mushi is a worm with a black head and red body. It invades the stomach and causes vomiting and diarrhea. It is known to come up into the host's mouth and poke its head out. Try to grab it, and you choke for air, but let go and it returns peacefully to the stomach.
The herbs goshuyu (Euodia rutaecarpa), shazenshi and mokko are useful in fighting Kakuran-no-mushi.